The reductions in both blood glucose and plasma insulin levels suggested that subchronic d-allulose treatment improved glucose tolerance at least partly by ameliorating insulin resistance in HFD-fed mice, consistent with previous findings 17
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SURMOUNT and STEP clinical trial data on weight plateau management
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(2012) reported that postmenopausal women with T2DM who took flavan-3-ols and isoflavones for a year exhibited significant reductions in estimated peripheral insulin resistance and persistent improvements in lipid profile and insulin sensitivity (155)