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Obesity was associated with poor functional outcome at three months (adjusted odds ratio [aOR] 2.66, 95% confidence interval [CI] 1.19-6.00) and a lower likelihood of excellent functional outcome at one year (aOR 0.44, 95% CI 0.22-0.86) (figure2)

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These concentrations of sertraline were based on reaching ~50% reduction in clonogenic survival when used as monotherapy