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J., Lambrix, V., Reichelt, M

Individuals with certain alleles at these loci may require higher doses or dual-compound therapy to achieve the same appetite suppression as others

In one case study, a woman with bipolar disorder felt an uncomfortable euphoria while taking semaglutide that resolved when she stopped the medication, suggesting that certain GLP-1s could impact mood in at least some individuals

Even small imbalances can significantly affect fertility