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This coupling stimulates adenylate cyclase (AC), particularly the AC8 isoform in pancreatic -cells, resulting in a rapid increase in cyclic adenosine monophosphate (cAMP) (Roger et al., 2011)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Page M.J., McKenzie J.E., Bossuyt P.M., Boutron I., Hoffmann T.C., Mulrow C.D., Shamseer L., Tetzlaff J.M., Akl E.A., Brennan S.E., et al

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