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Report severe nausea, vomiting lasting more than a few hours, severe abdominal pain, persistent constipation, or signs of pancreatitis (upper abdominal pain radiating to back, elevated amylase)

Your record should not start over each time

The growth area of melanoma is typically hypoxic and hypovascular, which is adverse to the arrival of conventional anti-tumor drugs [58], but provides an appropriate condition for the colonization of anaerobic or facultative anaerobic oncolytic bacteria

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Traditional first-line treatment is the standard R.I.C.E