The injection can be given at any time of day, with or without meals
In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition
E., Greinacher, A
Learn more MOTS-c Peptide Therapy MOTS-c is a mitochondrial-derived peptide studied for its role in metabolic regulation, glucose handling, fatty acid use, and cellular energy through the AMPK pathway
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