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This stimulates the pancreas to produce and release insulin

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There is also further ongoing research to understand the mechanisms of GIP agonism versus antagonism to decide on the optimal weight loss and antihyperglycemic approach

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Because it is a triple agonist that includes glucagon, it directly stimulates lipolysis and increases resting energy expenditure, resulting in significantly greater weight loss in head-to-head phase 2 trials

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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Ryskalin L., Lazzeri G., Flaibani M., Biagioni F., Gambardella S., Frati A., Fornai F

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