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In one study, it affected Egr , Nos , Srf , Vegfr , Akt1 , Plc, and Kras gene expression in the vessel that provides an alternative operating pathway (i.e., the left ovarian vein as the key for infrarenal occlusion-induced inferior vena cava syndrome in rats) (Vukojevic et al., 2018)

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On the other side , theres significant pushback from the scientific establishment