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Maintenance of efficacy for patients who had an initial response during the open-label period and then continued on VYVANSE during the 26-week double-blind randomized-withdrawal phase was demonstrated with VYVANSE being superior over placebo as measured by time to relapse

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Willesen et al., 1999

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One such biologic, Humira, is the top selling pharmaceutical drug in the world and as its market share increased, its list price soared 470%