For Wegovy, this involves starting at 0.25 mg weekly for 4 weeks, then increasing through 0.5 mg, 1 mg, 1.7 mg, and finally to the 2.4 mg maintenance dose, with each step lasting 4 weeks
GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids
Eat Balanced Meals Incorporate foods rich in: Fiber (e.g., leafy greens, beans, berries) Lean protein (e.g., chicken, tofu, eggs) Healthy fats (e.g., avocado, olive oil, nuts) These help promote satiety and stabilize blood sugar levels
Losing muscle means your metabolism slows
Exenatide, one of the first approved, extended the half-life enough to allow twice-daily injections