Nobiletin, a common natural flavonoid, has been found to activate mitophagy via AMPK and SIRT1 pathways, potentially alleviating D-galactose-induced mitochondrial damage in granulosa cells and delaying age-related apoptosis (Park et al., 2016
Hygum K, Harslof T, Jorgensen NR, Rungby J, Pedersen SB, Langdahl BL
Journal reference: Johnson B, Milstead M, Thomas O, et al
Known countermeasures to weight loss-associated bone loss include dietary factors, ensuring adequate protein, calcium, and vitamin D, along with participating in progressive resistance training (RT) to support skeletal muscle health and maintain long-term weight loss ( Statements Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation
PMID 7663973