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3 Possible causes of fertility problems problems include testicular problems resulting in abnormal sperm parameters, hormonal conditions, and problems with sperm transport

DOI: 10.3390/nu14091755

People with type 2 diabetes have lower levels of insulin secreted in the body

147 Leptin binds to the leptin receptor (LepRb) and activates JAK2/STAT3 pathway to decrease body weight and normalizes blood glucose concentration, meanwhile, JAK2 stimulates the phosphorylation of insulin receptor substrate (IRS1/2), then activates PI3K/Akt pathway and directly affect insulin action