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3,507 GLP-1RAs reduce liver fat accumulation by activating AMPK, which inhibits fatty acid synthesis enzymes and promotes fatty acid -oxidation, thus diminishing lipid droplet accumulation in hepatocytes

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Patients who discontinued their GLP-1 RA and had a weight measurement available within 60 days before discontinuation were followed up for up to 2 additional years to assess reinitiation of any GLP-1 RA

The FDAs post-marketing surveillance system collects data on side effects reported by doctors and patients