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10.1016/j.jgg.2014.06.002 J

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The excessive generation of free radicals within organisms can induce oxidative stress, thereby leading to the impairment of cell or tissue functions and subsequently resulting in various diseases such as inflammation, cancer, and neurodegenerative disorders 17

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Biochem J 409(1):205213 Kapeta S, Chondrogianni N, Gonos ES (2010) Nuclear erythroid factor 2 (Nrf2) mediated proteasome activation delays senescence in human fibroblasts

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