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A healthy diet typically provides the adequate intake (30 g per day for adults) needed for normal physiology

Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal, further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly (for parenteral supplementation) or daily (for oral supplementation)

If you have a vitamin B12 deficiency, you may receive injections daily or every other day to help replenish your B12 levels

In essence, adding Vitamins B6 and B12 ensures a comprehensive approach to managing diabetes and obesity, maximizing the benefits of your treatment plan

Summary: Vitamin B12 toxicity from supplementation is extremely rare, but persistently elevated serum levels may indicate underlying liver disease, kidney dysfunction, or haematological disorders requiring medical investigation