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Pfeiffer et al., 2011

& Holmberg, C

105,212 Hyperuricemia frequently coexists with insulin resistance, which can elevate the activity of the renin-angiotensin-aldosterone system and the sympathetic nervous system

If administered parentally, or if administered concurrently in the presence of an MAO inhibitor, elevated levels of plasma tyramine are taken up by presynaptic neuronal NET transporters which induces the release of norepinephrine