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doi:10.1007/s00421-021-04774-6 Addicott MA, Yang LL, Peiffer AM, Burnett LR, Burdette JH, Chen MY, Hayasaka S, Kraft RA, Maldjian JA, Laurienti PJ

5.3 Disease-specific determinants of perinatal glucocorticoid sensitivity Multiple perinatal complications have been associated with fetal/neonatal dysregulation of the HPA axis, cortisol metabolism, and tissue GR expression and function ( Table 3 )

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Introduction Commonly, the pleiotropic issue of healing (i.e., specifically, maintaining/reestablishing tissue integrity) remains a central challenge in pharmacology, particularly when the process is misdirected or not properly controlled [1]