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10.1016/j.lfs.2022.120753 Life Sci

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Losing weight reduces the inflammatory burden but the timeline is nonlinear, and the pathways that drive inflammation (particularly NF-B signalling) do not simply switch off as body fat declines

All of this data has clinical relevance: Polonikov , studying 4 cases of moderate to severe COVID-19, found that while the three patients with high normal plasma glutathione levels recovered quickly, the one with low glutathione levels, high plasma ROSs and ROS / GSH ratio was suffering from the most severe disease and, at the time of publication, was still ill

However, they can come with side effects such as nausea, vomiting, and in some cases, more serious gastrointestinal issues