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The 28-day timeline applies to Wegovy (single-dose) when stored at room temperature before use, not Ozempic

Non-Surgical Solutions & Supplements Nutritional support is essential during GLP-1 therapy, since appetite suppression can lead to inadequate protein and micronutrient intake

Adv Nutr 5:394403 Calabrese V, Scapagnini G, Ravagna A, Bella R, Butterfield DA, Calvani M, Pennisi G, Giuffrida Stella AM (2003) Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine