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Cazzola, M., Calzetta, L., Page, C., Jardim, J., Chuchalin, A.G., Rogliani, P., Matera, M.G

Higher doses or extended treatment plans typically increase the overall cost

This could explain why infection of mice with oral Trepomnema denticola bacteria induces Tau hyperphosphorylation and A accumulation in mice in the hippocampus with neuronal loss (Wu et al., 2022), and why filtrates of Helicobacter pylori bacteria induce Tau hyperphosphorylation in mouse neuroblastoma cells and rat brains via GSK-3 activation (Wang et al., 2014)

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Research highlights its role in enhancing t-cell regulation , promoting the maturation of T-cells into functional, balanced immune responders rather than dysregulated attackers