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Drug Shortage Status The FDA declared the tirzepatide shortage resolved in October 2024 and the semaglutide shortage resolved in February 2025

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Acknowledgements The authors would like to acknowledge the support provided by the Science, Technology & Innovation Funding Authority (STDF) in cooperation with the Egyptian Knowledge Bank (EKB) for funding the open access publication of this work

Options include holding the dose for an additional week, temporarily reducing the dose, adding supportive measures like specific supplements , or modifying meal timing and composition

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