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The cardioprotective effects appear independent of weight loss, suggesting direct cardiovascular benefits of GLP-1 receptor activation

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Mice immunized with the tocilizumab mimotope underwent UUO surgery showed reduced level of fibrosis, injury and apoptosis by down-regulating the pro-fibrotic proteins, alleviating the activation and differentiation of macrophage F4/80 + cells [133]

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High blood glucose makes AGEs, which build up in blood vessels

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