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Efficacy-wise, AOD-9604 produces modest results (2-3 kg over 12 weeks in trials) compared to GLP-1 agonists dramatic weight loss

Additionally, AOD9604 may have effects on fatty acid oxidation in peripheral tissues, enhancing the utilization of released free fatty acids for energy production rather than allowing them to be re-esterified and stored

Individual response varies considerably, with some noticing effects earlier than others

It was identified through a medicinal chemistry programme at the University of Texas Health Science Center as the lead NNMT inhibitor candidate among a series of 1-methylquinolinium analogues bearing primary amine substitutions, selected for its combination of high passive membrane permeability (confirmed in PAMPA assays), high active transport membrane permeability (confirmed in bidirectional Caco-2 cell assays), potent NNMT inhibitory activity, and high selectivity including confirmed absence of inhibitory effects on related SAM-dependent methyltransferases or enzymes in the NAD+ salvage pathway

Injections are quick and convenient and can often be added to your regular visit